G protein variation in respiratory syncytial virus group A does not correlate with clinical severity.

نویسندگان

  • A H Brandenburg
  • R van Beek
  • H A Moll
  • A D Osterhaus
  • E C Claas
چکیده

Respiratory syncytial virus group A strain variations of 28 isolates from The Netherlands collected during three consecutive seasons were studied by analyzing G protein sequences. Several lineages circulated repeatedly and simultaneously during the respective seasons. No relationships were found between lineages on the one hand and clinical severity or age on the other.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Interferon alfa, infectious virus, and virus antigen secretion in respiratory syncytial virus infections of graded severity.

Interferon alfa was measured by an immunoradiometric assay in the nasopharyngeal secretions of a group of infants admitted to hospital with respiratory syncytial virus infection. Virus replication in the upper respiratory tract was assessed by infectivity assay and by an enzyme linked immunoadsorbent assay for the viral fusion protein on the same nasopharyngeal secretions. All infants were exam...

متن کامل

The Frequency Distribution of Parainfluenza, Adeno and Respiratory Syncytial Virus Infections in Children below 2 Years Old with Bronchiolititis, by Multiplex Polymerase Chain Reaction Method, Afzalipoor Hospital, Kerman, 2006

Background & Aims: Acute respiratory infections are common cause of mortality during childhood. This study was designed to determine the incidence of adenovirus, parainfluenza virus and respiratory syncytial virus in respiratory infections by Multiplex PCR method. Methods: This study included 168 children under 2 years of age with clinical diagnosis of bronchiolitis. Nasopharyngeal specimens we...

متن کامل

نقش ویروس های سن سی شیال تنفسی و آنفلوآنزا در عفونت های حاد مجاری تنفسی تحتانی کودکان استان مازندران در سال 1381

Background and purpose: The acute lower respiratory tract infective agents in children are different. The rate of their role in causing infection differs with the age of patients, season, geographical areas and diagnostic methods. The aim of this study is to determine the rate of the role of respiratory syncytial and influenza viruses in Mazandaranian children infected with acute lower res...

متن کامل

Influenza A virus among the hospitalized young children with acute respiratory infection. Is influenza A co infected with respiratory syncytial virus?

Background: Both influenza A virus (IAV) and respiratory syncytial virus (RSV) cause acute respiratory infection (ARI) in infants and young children. This study was conducted to determine Influenza A virus and its co infection with RSV among the hospitalized children with ARI. Methods: A total of 153 throat samples of the hospitalized young children aged between below one year and 5 years with...

متن کامل

High pneumococcal density correlates with more mucosal inflammation and reduced respiratory syncytial virus disease severity in infants.

BACKGROUND Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infections in infants. A small percentage of the infected infants develops a severe infection, while most of these severely ill patients were previously healthy. It remains unclear why these children develop severe RSV infections. In this study, we investigate whether pneumococcal nasopharyngeal carria...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of clinical microbiology

دوره 38 10  شماره 

صفحات  -

تاریخ انتشار 2000